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Vertex Pharmaceuticals Is A Global Biotechnology Company That Discovers And Develops Small-Molecule Drugs For The Treatment Of Serious Diseases. Its Key Drugs Are Kalydeco, Orkambi, Symdeko, And Trikafta/Kaftrio, And Alyftrek For Cystic Fibrosis, Where Vertex Therapies Remain The Standard Of Care Globally. Vertex Is Focused On Diversifying Its Portfolio Through Casgevy (Gene-Editing Therapy For Beta Thalassemia And Sickle-Cell Disease), Journavx (Non-Opioid Pain Drug For Moderate-To-Severe Acute Pain), And Palsonify (For Acromegaly). Additionally, Vertex Is Evaluating Small-Molecule Inhibitors Of Apol1-Mediated Kidney Diseases, Cell Therapies To Deliver A Functional Cure For Type 1 Diabetes, Povetacicept (For Iga Nephropathy).