SPRB · SPRUCE BIOSCIENCES, INC.

Spruce Biosciences Inc Is A Late-Stage Biopharmaceutical Company Focused On Developing And Commercializing Novel Therapies For Rare Endocrine Disorders With Unmet Medical Needs. The Company Develops Biologics And Small-Molecule Product Candidates Aimed At Addressing Diseases With Unmet Medical Needs And Limited Or No Approved Therapies. Its Product Candidate, Ta-Ert For The Treatment Of Mucopolysaccharidosis Type Iiib (Mps Iiib), Is A Fusion Protein Comprised Of Recombinant Human Alpha-N-Acetylglucosaminidase (Rhnaglu) Intended As An Enzyme Replacement Therapy For Patients Who Lack Rhnaglu Enzyme Activity. Ta-Ert Is Designed To Restore Rhnaglu Enzyme Activity In The Central Nervous System Following Intracerebroventricular Injection And Promote Clearance Of Heparan Sulfate In The Brain.